Trimethoprim is a popular and effective synthetic drug that is mainly used to treat the bacterial infection but its primary action is to cure cystitis. It is chiefly used to treat uncomplicated urinary tract infections (UTI) due to susceptible bacteria such as Escherichia coli, Proteus mirabilis, Klebsiellapneumoniae, Enterobacter species, and coagulase-negative Staphylococcus speciesuncomplicated urinary tract infections (UTI) due to susceptible bacteria such as Escherichia coli, Proteus mirabilis, Klebsiellapneumoniae, Enterobacter species, and coagulase-negative Staphylococcus species.
Importance of trimethoprim
Trimethoprim may inhibit the hepatic metabolism of phenytoin and for cystitis treatment. Trimethoprim (trimethoprim (trimethoprim tablet) tablet), given at a common clinical dosage, increased the phenytoin half-life by 51% and decreased the phenytoin metabolic clearance rate by 30%. When administering these drugs concurrently, one should be alert for possible excessive phenytoin effect.
Risk of anemia and other severe diseases
Trimethoprim can cause anemia because of the deficiency of folic acid, but it is not too severe. It will long till the usage of this drug and after the use of this antibiotic is stopped, you will not feel anemia. Patients who are folate-deficient, such as malnourished, suffering from cystitis, alcoholic, geriatric, or pregnant females, may be at greater risk for developing anemia with trimethoprim. Warning signs of anemia include white or bluish fingernails and unusual tiredness and weakness. Prolonged therapy can result in low platelet counts, low white blood cell counts, and other toxic effects on the blood cells. You may also face the below mentioned diseases:
- Serious allergic reactions
- Exfoliative dermatitis
- Stevens-Johnson syndrome
- Cholestatic jaundice
- C. Difficile diarrhea
What are some of the Key facts about trimethoprim?
Trimethoprim is usually taken twice a day to treat infections such as cystitis. For most infections, you’ll feel better within a few days. Side effects may include itching or a mild skin rash, but are usually mild and short-lived. You can drink alcohol while taking trimethoprim. There are no brand names for this medicine at the moment.
Dosage of trimethoprim
The usual oral adult dosage is 100 mg of trimethoprim every 12 hours or 200 mg trimethoprim (trimethoprim (trimethoprim tablet) tablet) (two 100 mg tablets) every 24 hours, each for 10 days, you can get this medicine by hovering to https://www.ukmeds.co.uk/treatments/cystitis/trimethoprim-200mg-6-tablets/. The use of trimethoprim (trimethoprim (trimethoprim tablet) tablet) in patients with a creatinine clearance of less than 15 mL/min is not recommended. For patients with a creatinine clearance of 15 to 30 mL/min, the dose should be 50 mg every 12 hours.